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WebNov 19, 2014 · Our gut microbiota is important for many biological functions in the body, including intestinal development, barrier integrity and function (1, 2), metabolism (3, 4), the immune system (), and the central nervous system (CNS).The effects of the gut microbiota on brain physiology include synaptogenesis, regulation of neurotransmitters and … WebApr 11, 2024 · The gut microbiota forms a complex, dense axis with the autonomic and enteric nervous systems. ... Disturbed integrity of the intestinal barrier caused by dysbiosis leads to an increase in bacterial translocation and metabolic endotoxemia, which activates the hepatic TLR system, thus the local inflammatory response of the liver . Bacterial ...
WebApr 14, 2024 · Heart failure is a worldwide health problem with important consequences for the overall wellbeing of affected individuals as well as for the healthcare system. Over … WebDec 16, 2024 · According to Anderson-Haynes, the gut is responsible not only for digestion, but also for assisting functions such as hormone regulation and immune system activity. …
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WebFeb 26, 2024 · Conversely, activation of epithelial TLR4 causes loss of barrier integrity and a leaky gut in both mouse models and human IEC lines 94,103,104 through a mechanism that involves upregulation of ...
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